2-Methyltetrahydrofuran

Names

[ CAS No. ]:
96-47-9

[ Name ]:
2-Methyltetrahydrofuran

[Synonym ]:
2-methyl tetrahydrofuran
2-Methylfuranidine
2-methyl-THF
EINECS 202-507-4
METHF
2-Methyletrahydrofuran
methyl-tetrahydrofuran
2-METHYLTETRAHYDROFURA
2-MeTHF
TETRAHYDROSILVAN
2-Methyltetrahydrofu
Tetrahydrosylvan
MFCD00005367

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
79.9±0.0 °C at 760 mmHg

[ Melting Point ]:
-136 °C

[ Molecular Formula ]:
C₅H₁₀O

[ Molecular Weight ]:
86.132

[ Flash Point ]:
-11.1±0.0 °C

[ Exact Mass ]:
86.073166

[ PSA ]:
9.23000

[ LogP ]:
0.82

[ Vapour Pressure ]:
96.8±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.411

[ Stability ]:
Stable, but highly flammable. Incompatible with oxidizing agents, strong acids, strong bases. May form explosive peroxides in storage, so often supplied with an inhibitor added.

[ Water Solubility ]:
15 g/100 mL (25 C)

[ Freezing Point ]:
-136℃

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LU2800000

CHEMICAL NAME :: Furan, 2-methyl-tetrahydro-

CAS REGISTRY NUMBER :: 96-47-9

BEILSTEIN REFERENCE NO. :: 0102448

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C5-H10-O

MOLECULAR WEIGHT :: 86.15

WISWESSER LINE NOTATION :: T5OTJ B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,786,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,395,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 4500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,395,1969

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302-H315-H318

[ Precautionary Statements ]:
P210-P280-P301 + P312 + P330-P305 + P351 + P338 + P310-P403 + P235

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11;R19;R36/37

[ Safety Phrases ]:
S16-S23-S39-S33-S26

[ RIDADR ]:
UN 2536 3/PG 2

[ WGK Germany ]:
2

[ RTECS ]:
LU2800000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2932190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

On-line monitoring of continuous flow chemical synthesis using a portable, small footprint mass spectrometer.

J. Am. Soc. Mass Spectrom. 25(10) , 1794-802, (2014)

For on-line monitoring of chemical reactions (batch or continuous flow), mass spectrometry (MS) can provide data to (1) determine the fate of starting materials and reagents, (2) confirm the presence ...

Efficient synthesis of phosphatidylserine in 2-methyltetrahydrofuran.

J. Biotechnol. 163(1) , 45-9, (2013)

2-Methyltetrahydrofuran has recently been described as a promising and green solvent. Herein, it was successfully used as the reaction medium for enzyme-mediated transphosphatidylation of phosphatidyl...

Temperature dependence of charge separation and recombination in porphyrin oligomer-fullerene donor-acceptor systems.

J. Am. Chem. Soc. 133(25) , 9863-71, (2011)

Electron-transfer reactions are fundamental to many practical devices, but because of their complexity, it is often very difficult to interpret measurements done on the complete device. Therefore, stu...