2,4(1H,3H)-Pyrimidinedione,3-methyl-5-b-D-ribofuranosyl-

Names

[ Name ]:
2,4(1H,3H)-Pyrimidinedione,3-methyl-5-b-D-ribofuranosyl-

Biological Activity

[Description]:

3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.576g/cm3

[ Molecular Formula ]:
C₁₀H₁₄N₂O₆

[ Molecular Weight ]:
258.23

[ Exact Mass ]:
258.08500

[ PSA ]:
124.78000

[ Index of Refraction ]:
1.618

2,4(1H,3H)-Pyrimidinedione,3-methyl-5-b-D-ribofuranosyl-

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds