Biphenyl dimethyl dicarboxylate

Names

[ CAS No. ]:
792-74-5

[ Name ]:
Biphenyl dimethyl dicarboxylate

[Synonym ]:
EINECS 212-341-4
MFCD00017201
Dimethyl (1,1'-biphenyl)-4,4'-dicarboxylate
Dimethyl biphenyl-4,4'-dicarboxylate
(1,1'-Biphenyl)-4,4'-dicarboxylic acid, dimethyl ester
Biphenyl dimethyl dicarboxylate
Dimethyl 4,4'-biphenyldicarboxylate
methyl 4-(4-methoxycarbonylphenyl)benzoate
[1,1'-Biphenyl]-4,4'-dicarboxylic acid, dimethyl ester
4,4'-Biphenyldicarboxylic acid, dimethyl ester

Biological Activity

[Description]:

Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a hepatoprotectant obtained from Schizandra fructus and may induce a signal transduction similar to that associated with IFN[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Joo SS, et al. Interferon signal transduction of biphenyl dimethyl dicarboxylate/amantadine and anti-HBV activity in HepG2 2.2.15. Arch Pharm Res. 2006 May;29(5):405-11.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
407.0±38.0 °C at 760 mmHg

[ Melting Point ]:
213-215 °C(lit.)

[ Molecular Formula ]:
C₁₆H₁₄O₄

[ Molecular Weight ]:
270.280

[ Flash Point ]:
204.7±25.2 °C

[ Exact Mass ]:
270.089203

[ PSA ]:
52.60000

[ LogP ]:
3.71

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.559

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2917399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2917399090

[ Summary ]:
2917399090 aromatic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Synthesis and properties of luminophores derived from fluorinated biphenyls. Ol'khovik VK, et al.

Russ. J. Org. Chem. 44(8) , 1172-79, (2008)

Dimethyl biphenyl-4, 4'-dicarboxylate. Ritzerfeld V, et al.

Acta Crystallogr. Sect. E Struct. Rep. Online 65(7) , 1677, (2009)