4-Bromoanisole
Names
[ CAS No. ]:
104-92-7
[ Name ]:
4-Bromoanisole
[Synonym ]:
Benzene, 1-bromo-4-methoxy-
Of BroMoanisole
1-Bromo-4-methoxybenzene
Anisole, p-bromo-
p-Methoxyphenyl Bromide
p-anisylbromide
p-bromoanisol
Anisyl bromide
4-methoxyphenyl bromide
4-Bromoanisole
1-bromo-4-methoxy-benzene
4-BROMO ANISOL
4-methoxy-1-bromobenzene
p-Bromanisole
anisole, 4-bromo-
EINECS 203-252-1
4-Bromophenyl methyl ether
p-bromoanisole
MFCD00000097
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
223.0±0.0 °C at 760 mmHg
[ Melting Point ]:
9-10 °C(lit.)
[ Molecular Formula ]:
C7H7BrO
[ Molecular Weight ]:
187.034
[ Flash Point ]:
94.4±0.0 °C
[ Exact Mass ]:
185.968018
[ PSA ]:
9.23000
[ LogP ]:
3.16
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.539
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
immiscible
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BZ8501000
- CHEMICAL NAME :
- Anisole, p-bromo-
- CAS REGISTRY NUMBER :
- 104-92-7
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C7-H7-Br-O
- MOLECULAR WEIGHT :
- 187.05
- WISWESSER LINE NOTATION :
- ER DO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 44(12),19,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1186 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 44(12),19,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81912 No. of Facilities: 14 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 392 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
Xn
[ Safety Phrases ]:
S23-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
BZ8501000
[ Hazard Class ]:
6.1
[ HS Code ]:
29093038
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2909309090
[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Environ. Sci. Technol. 49(8) , 4937-45, (2015)
When bromide-containing waters are chlorinated, conventional wisdom typically assumes HOBr is the only active brominating agent. Several additional and often-overlooked brominating agents (including B...
Hypobromous acid, a powerful endogenous electrophile: Experimental and theoretical studies.J. Inorg. Biochem. 146 , 61-8, (2015)
Hypobromous acid (HOBr) is an inorganic acid produced by the oxidation of the bromide anion (Br(-)). The blood plasma level of Br(-) is more than 1,000-fold lower than that of chloride anion (Cl(-)). ...
Pd-catalyzed carbonylative α-arylation of aryl bromides: scope and mechanistic studies.Chemistry 19(52) , 17926-38, (2013)
Reaction conditions for the three-component synthesis of aryl 1,3-diketones are reported applying the palladium-catalyzed carbonylative α-arylation of ketones with aryl bromides. The optimal condition...