MAO-B-IN-27

Names

[ Name ]:
MAO-B-IN-27

Biological Activity

[Description]:

MAO-B-IN-27 (Compound 12c) is a monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-27 has potent and selective MAO-B inhibitory effect for hMAO-B with an IC50 values of 8.9 nM. MAO-B-IN-27 can be used for the research of parkinson's disease (PD)[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase

Research Areas >> Neurological Disease

[Target]

IC50: 8.9 nM (hMAO-B)[1].

[References]

[1]. Yeon SK, et al. Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy. Bioorg Med Chem. 2018 Jan 1;26(1):232-244.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₇ClF₃NO

[ Molecular Weight ]:
331.76

Related Compounds

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