788824-83-9

788824-83-9 structure

Name: MAO-B-IN-27
Chemical Name: MAO-B-IN-27
CAS Number: 788824-83-9
Molecular Formula: C₁₆H₁₇ClF₃NO
Molecular Weight: 331.76
Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
Create Date: 2024-01-11 22:27:10
Modify Date: 2024-01-11 22:27:10
MAO-B-IN-27 (Compound 12c) is a monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-27 has potent and selective MAO-B inhibitory effect for hMAO-B with an IC50 values of 8.9 nM. MAO-B-IN-27 can be used for the research of parkinson's disease (PD)[1].

Name	MAO-B-IN-27

Description	MAO-B-IN-27 (Compound 12c) is a monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-27 has potent and selective MAO-B inhibitory effect for hMAO-B with an IC50 values of 8.9 nM. MAO-B-IN-27 can be used for the research of parkinson's disease (PD)[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	IC50: 8.9 nM (hMAO-B)[1].
References	[1]. Yeon SK, et al. Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy. Bioorg Med Chem. 2018 Jan 1;26(1):232-244.

Molecular Formula	C₁₆H₁₇ClF₃NO
Molecular Weight	331.76