L-(−)-Arabitol

Names

[ Name ]:
L-(−)-Arabitol

[Synonym ]:
L-ARA-OL
(2S,4S)-pentane-1,2,3,4,5-pentol
L(-)-ARABIT
L-(-)-Arabitol
MFCD00064290
L-Arabite
L-Arabinitol
arabinitol
EINECS 231-582-6
(2S,4S)-1,2,3,4,5-Pentanepentol
Arabitol
(2S,4S)-1,2,3,4,5-Pentanpentol
L-threo-pentitol
L-(-)arabinol
L-arabinol
L-ARABITINOL
Arabinitol, L-
L-Arabitol
L-lyxitol

Biological Activity

[Description]:

L-Arabinitol is a potential biomarker for the comsuption of the food products such as sweet potato, deerberry, moth bean, and is also associated with Alzheimer's disease and ribose-5-phosphate isomerase deficiency.

[Related Catalog]:

Natural Products >> Others

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[References]

[1]. Shetty HU, et al. Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease. Clin Chem. 1996 Feb;42(2):298-302.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
494.5±40.0 °C at 760 mmHg

[ Melting Point ]:
101-104ºC(lit.)

[ Molecular Formula ]:
C₅H₁₂O₅

[ Molecular Weight ]:
152.146

[ Flash Point ]:
261.9±21.9 °C

[ Exact Mass ]:
152.068466

[ PSA ]:
101.15000

[ LogP ]:
-3.77

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.571

[ Storage condition ]:
Refrigerator (+4°C)

[ Water Solubility ]:
H2O: 0.1 g/mL, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Diagnostic use of cerebral and extracerebral oxysterols.

Clin. Chem. Lab Med. 42(2) , 186-91, (2004)

24S-Hydroxycholesterol (24OHC) and 27-hydroxycholesterol (27OHC) are two structurally similar oxysterols of different origins--the former almost exclusively formed in the brain and the latter formed t...

The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer's disease.

Neurobiol. Aging 23(3) , 383-8, (2002)

There is evidence that increased blood concentrations of homocysteine may be a risk factor for Alzheimer's disease. (E)-4-hydroxy-2-nonenal (HNE) is a neurotoxic product of lipid peroxidation that is ...

Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease.

Clin. Chem. 42(2) , 298-302, (1996)

Previous studies suggest the presence of increased concentrations of cerebral myo-inositol in Alzheimer disease (AD). To characterize this abnormality further, we quantified myo-inositol and several o...