3'-fluoro-3'-deoxyadenosine

Names

[ Name ]:
3'-fluoro-3'-deoxyadenosine

[Synonym ]:
3'-F-dA
3'-Deoxy-3'-fluoroadenosine
3'-Fluoro-3'-deoxyadenosine
Adenosine,3'-deoxy-3'-fluoro

Biological Activity

[Description]:

3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Boiling Point ]:
628.6°C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₂FN₅O₃

[ Molecular Weight ]:
269.23

[ Flash Point ]:
334°C

[ Exact Mass ]:
269.09200

[ PSA ]:
119.31000

Related Compounds

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