3'-FLUORO-3'-DEOXYCYTIDINE

Names

[ Name ]:
3'-FLUORO-3'-DEOXYCYTIDINE

[Synonym ]:
3'-deoxy-3'-fluorocytidine
Cytidine,3'-deoxy-3'-fluoro
3'-fluoro-3'-deoxycytidine
Cytidine,3'-deoxy-3'-fluoro-(9CI)

Biological Activity

[Description]:

3′-Deoxy-3′-fluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.82g/cm3

[ Boiling Point ]:
500.1ºC at 760mmHg

[ Molecular Formula ]:
C₉H₁₂FN₃O₄

[ Molecular Weight ]:
245.21

[ Flash Point ]:
256.2ºC

[ Exact Mass ]:
245.08100

[ PSA ]:
111.59000

[ Vapour Pressure ]:
4.27E-12mmHg at 25°C

[ Index of Refraction ]:
1.697

3'-FLUORO-3'-DEOXYCYTIDINE

Names

Biological Activity

Chemical & Physical Properties

Related Compounds