9-(3'-fluoro-3'-deoxyxylofuranosyl)adenine

Names

[ CAS No. ]:
20535-16-4

[ Name ]:
9-(3'-fluoro-3'-deoxyxylofuranosyl)adenine

[Synonym ]:
9-Fdxa
9-(3'-Fluoro-3'-deoxyxylofuranosyl)adenine

Biological Activity

[Description]:

3’-Deoxy-3’-fluoro-xyloadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₂FN₅O₃

[ Molecular Weight ]:
269.23

[ Exact Mass ]:
285.08700

[ PSA ]:
139.54000

9-(3'-fluoro-3'-deoxyxylofuranosyl)adenine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds