Fmoc-Ile-OH

Names

[ CAS No. ]:
71989-23-6

[ Name ]:
Fmoc-Ile-OH

[Synonym ]:
L-Isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine
N-((9H-Fluoren-9-ylmethoxy)carbonyl)-L-isoleucine
EINECS 276-255-9
MFCD00037125
N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine
N-Fmoc-Ile-OH ( N-Fmoc-L-isoleucine)
FMOC-L-Isoleucine
Fmoc-Ile-OH

Biological Activity

[Description]:

Fmoc-Ile-OH is an isoleucine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
559.8±33.0 °C at 760 mmHg

[ Melting Point ]:
145-147 °C(lit.)

[ Molecular Formula ]:
C₂₁H₂₃NO₄

[ Molecular Weight ]:
353.412

[ Flash Point ]:
292.4±25.4 °C

[ Exact Mass ]:
353.162720

[ PSA ]:
75.63000

[ LogP ]:
4.95

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.583

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Complete ON/OFF photoswitching of the motility of a nanobiomolecular machine.

ACS Nano 8(5) , 4157-65, (2014)

To apply motor proteins as natural nanomolecular machines to transporting systems in nanotechnology, complete temporal control over ON/OFF switching of the motility is necessary. We have studied the p...

Design and synthesis of newN-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides as anti-inflammatory agents

Eur. J. Med. Chem. 44 , 1933-40, (2009)

Twenty-four new dipeptide analogs ( 1– 24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in respo...