Methyl isovanillate

Names

[ Name ]:
Methyl isovanillate

[Synonym ]:
Methyl 3-hydroxy-4-methoxybenzenecarboxylate
Isovanillic Acid Methyl Ester
MFCD01321262
1OVR CQ DO1
Methyl isovanillate
3-hydroxy-4-methoxy-benzoic acid methyl ester
3-Hydroxy-4-methoxybenzoic acid methyl ester
Methyl 3-hydroxy-4-methoxybenzoate
methyl 3-hydroxy-4-methoxy-benzoate
Benzoic acid, 3-hydroxy-4-methoxy-, methyl ester
5-carbomethoxy-2-methoxyphenol

Biological Activity

[Description]:

Methyl isovanillate is a secondary metabolite isolated from Vitex agnus-castus[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Alper GÖKBULUT, et al. Radical Scavenging Activity and Vitexin Content of Vitex agnus-castus Leaves and Fruits. FABAD J. Pharm. Sci. 35, 85-91, 2010

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
327.7±22.0 °C at 760 mmHg

[ Melting Point ]:
64-67ºC

[ Molecular Formula ]:
C₉H₁₀O₄

[ Molecular Weight ]:
182.173

[ Flash Point ]:
132.8±15.8 °C

[ Exact Mass ]:
182.057907

[ PSA ]:
55.76000

[ LogP ]:
1.75

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.534

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk).

Bioorg. Med. Chem. Lett. 21 , 3152-3158, (2011)

Continued examination of substituted 6-arylquinazolin-4-amines as Clk4 inhibitors resulted in selective inhibitors of Clk1, Clk4, Dyrk1A and Dyrk1B. Several of the most potent inhibitors were validate...