4,4'-Methylenediphenol

Names

[ CAS No. ]:
620-92-8

[ Name ]:
4,4'-Methylenediphenol

[Synonym ]:
bisphenol F
4,4'-Methylenediphenol
Phenol, 4,4'-methylenebis-
4,4'-Methandiyldibenzolol
4,4'-methylenebis-phenol
EINECS 210-658-2
MFCD00002385
4,4'-DIHYDROXYDIPHENYLMETHANE
4,4'-methanediyldiphenol
4,4'-methylenebis(phenol)
4-[(4-hydroxyphenyl)methyl]phenol

Biological Activity

[Description]:

4,4'-Dihydroxydiphenylmethane is a phenolic derivative with antioxidant activities[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. L Yi-Ming, et al. New Phenolic Derivatives from Galeola faberi. Planta Med. 1993 Aug;59(4):363-5.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
390.0±22.0 °C at 760 mmHg

[ Melting Point ]:
162-164 °C

[ Molecular Formula ]:
C₁₃H₁₂O₂

[ Molecular Weight ]:
200.233

[ Flash Point ]:
192.9±16.9 °C

[ Exact Mass ]:
200.083725

[ PSA ]:
40.46000

[ LogP ]:
2.73

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.635

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL9625000

CHEMICAL NAME :: Phenol, 4,4'-methylenebis-

CAS REGISTRY NUMBER :: 620-92-8

BEILSTEIN REFERENCE NO. :: 2049425

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C13-H12-O2

MOLECULAR WEIGHT :: 200.25

WISWESSER LINE NOTATION :: QR D1R DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4950 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
SL9625000

[ HS Code ]:
2907299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2907299090

[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

Articles

Determination of bisphenols in beverages by mixed-mode solid-phase extraction and liquid chromatography coupled to tandem mass spectrometry.

J. Chromatogr. A. 1422 , 230-8, (2015)

Facing growing restrictions on the use of bisphenol A in food contact materials, several bisphenol analogs are arising as major alternatives to replace this chemical in most of its applications. This ...

A simple method for the enrichment of bisphenols using boron nitride.

Food Chem. 194 , 149-55, (2015)

A simple solid-phase extraction method for the enrichment of 5 bisphenol derivatives using hexagonal boron nitride (BN) was developed. BN was applied to concentrate bisphenol derivatives in spiked wat...

Screening of bisphenol A, triclosan and paraben analogues as modulators of the glucocorticoid and androgen receptor activities.

Toxicol. In Vitro 29(1) , 8-15, (2014)

A homeostasis of the glucocorticoid and androgen endocrine system is essential to human health. Their disturbance can lead to various diseases, for example cardiovascular, inflammatory and autoimmune ...

Related Compounds

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