2-Allylphenol

Names

[ Name ]:
2-Allylphenol

[Synonym ]:
MFCD00002250
O-ALLYLPHENOL
o-allyl-pheno
ORTHO-ALLYLPHENOL
2-(2-propenyl)-pheno
EINECS 217-119-0
2-ALLYLPHENOL
ALLYLPHENOL-2
allylphenol
Phenol,o-allyl
2-(2-propenyl)phenol

Chemical & Physical Properties

[ Density]:
1.028 g/mL at 25 °C(lit.)

[ Boiling Point ]:
220 °C(lit.)

[ Melting Point ]:
-6 °C

[ Molecular Formula ]:
C₉H₁₀O

[ Molecular Weight ]:
134.17500

[ Flash Point ]:
192 °F

[ Exact Mass ]:
134.07300

[ PSA ]:
20.23000

[ LogP ]:
2.12070

[ Vapour Pressure ]:
0.0783mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.546(lit.)

[ Water Solubility ]:
7 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SJ3850000

CHEMICAL NAME :: Phenol, o-allyl-

CAS REGISTRY NUMBER :: 1745-81-9

BEILSTEIN REFERENCE NO. :: 0742121

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C9-H10-O

MOLECULAR WEIGHT :: 134.19

WISWESSER LINE NOTATION :: QR B2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536203 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8400 mg/kg/30W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 19,413,1959

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3360 mg/kg/12W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 19,413,1959

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311-H314

[ Precautionary Statements ]:
P280-P301 + P310-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26-S36/37/39-S45-S24/25-S23

[ RIDADR ]:
UN 2923 8/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
SJ3850000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29071900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 29071900

Articles

Inhibition of rat, mouse, and human glutathione S-transferase by eugenol and its oxidation products.

Chem. Biol. Interact. 99(1-3) , 85-97, (1996)

The irreversible and reversible inhibition of glutathione S-transferases (GSTs) by eugenol was studied in rat, mouse and man. Using liver cytosol of human, rat and mouse, species differences were foun...

Isolation of an unusual metabolite 2-allyloxyphenol from a marine actinobacterium, its biological activities and applications.

Appl. Microbiol. Biotechnol. 86(1) , 109-17, (2010)

A marine actinobacterium isolated from the Bay of Bengal, India and previously found to be producing an antimicrobial and cytotoxic terpenoid was further investigated for antimicrobial metabolites. Th...

Inhibitory effect of bionic fungicide 2-allylphenol on Botrytis cinerea (Pers. ex Fr.) in vitro.

Pest Manag. Sci. 65(12) , 1337-43, (2009)

2-Allylphenol is a registered fungicide in China to control fungal diseases on tomato, strawberry and apple. It is synthetic and structurally resembles the active ingredient ginkgol isolated from Gink...