indophenol

Names

[ CAS No. ]:
500-85-6

[ Name ]:
indophenol

[Synonym ]:
4-(4-hydroxyphenyl)iminocyclohexa-2,5-dien-1-one
EINECS 207-913-5
[1,4]Benzochinon-mono-(4-hydroxy-phenylimin)
Benzochinon-(1.4)-mono-(4-oxy-anil)
[1,4]benzoquinone-mono-(4-hydroxy-phenylimine)
MFCD00001621
INDOPHENOL
4-((4-Hydroxyphenyl)imino)-2,5-cyclohexadien-1-one
2,5-Cyclohexadien-1-one,4-[(4-hydroxyphenyl)imino]
N-(4-Hydroxyphenyl)-p-benzoquinone monoimine

Chemical & Physical Properties

[ Density]:
1.18g/cm3

[ Boiling Point ]:
360ºC at 760mmHg

[ Melting Point ]:
>300 °C(lit.)

[ Molecular Formula ]:
C₁₂H₉NO₂

[ Molecular Weight ]:
199.20500

[ Flash Point ]:
171.5ºC

[ Exact Mass ]:
199.06300

[ PSA ]:
49.66000

[ LogP ]:
2.15980

[ Index of Refraction ]:
1.6

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU5778000

CHEMICAL NAME :: 2,5-Cyclohexadien-1-one, 4-((4-hydroxyphenyl)imino)-

CAS REGISTRY NUMBER :: 500-85-6

LAST UPDATED :: 199706

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C12-H9-N-O2

MOLECULAR WEIGHT :: 199.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHBUA9 Pharmaceutical Bulletin. (Tokyo, Japan) V.1-5, 1953-57. For publisher information, see CPBTAL. Volume(issue)/page/year: 3,337,1955

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
GU5778000

[ HS Code ]:
2925290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors.

Bioorg. Med. Chem. Lett. 19 , 972-5, (2009)

Plasmodium falciparum NDH2 (pfNDH2) is a non-proton pumping, rotenone-insensitive alternative enzyme to the multi-subunit NADH:ubiquinone oxidoreductases (Complex I) of many other eukaryotes. Recombin...

A mathematical model to predict protein wash out kinetics during whole-lung lavage in autoimmune pulmonary alveolar proteinosis.

Am. J. Physiol. Lung Cell. Mol. Physiol. 308(2) , L105-17, (2015)

Whole-lung lavage (WLL) remains the standard therapy for pulmonary alveolar proteinosis (PAP), a process in which accumulated surfactants are washed out of the lung with 0.5-2.0 l of saline aliquots f...

Comparison of colorimetric and membrane introduction mass spectrometry techniques for chloramine analysis.

Water Res. 41(14) , 3097-102, (2007)

Three methods for the determination of chloramines in water were compared using pH-buffered nanopure water and natural organic matter (NOM) solutions. We investigated whether the N,N-diethyl-p-phenyle...