Quinolin-5-amine

Names

[ CAS No. ]:
611-34-7

[ Name ]:
Quinolin-5-amine

[Synonym ]:
quinolin-5-amine
5-Quinolinamine
5-Quinolinamine (9CI)
5-amino-quinoline
5-amino-quinolin
Chinolin-5-amin
EINECS 210-266-1
5-Aminoquinoline
Quinolin-5-ylamine
5-Quinolylamine
MFCD00006797
5-aminoqionoline

Biological Activity

[Description]:

Quinolin-5-amine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
310.0±0.0 °C at 760 mmHg

[ Melting Point ]:
106-109 °C(lit.)

[ Molecular Formula ]:
C₉H₈N₂

[ Molecular Weight ]:
144.17

[ Flash Point ]:
171.5±8.1 °C

[ Exact Mass ]:
144.068741

[ PSA ]:
38.91000

[ LogP ]:
0.92

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.708

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA9625000

CHEMICAL NAME :: Quinoline, 5-amino-

CAS REGISTRY NUMBER :: 611-34-7

BEILSTEIN REFERENCE NO. :: 0114479

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H8-N2

MOLECULAR WEIGHT :: 144.19

WISWESSER LINE NOTATION :: T66 BNJ GZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex)

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 16 ug/well

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,429,1981

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VA9625000

[ Packaging Group ]:
III

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Metabolic and radiolytic reduction of 4-alkylamino-5-nitroquinoline bioreductive drugs. Relationship to hypoxia-selective cytotoxicity.

Biochem. Pharmacol. 48(8) , 1593-604, (1994)

The 4-alkylamino-5-nitroquinolines (5NQs) are a new series of bioreductive drugs that exhibit varying degrees of selective toxicity (up to 60-fold) under hypoxic conditions in cell culture. This study...

Quantum chemical and spectroscopic investigations of 5-aminoquinoline.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 74(5) , 1215-23, (2009)

The Fourier transform infrared (FTIR) and FT-Raman spectra of 5-aminoquinoline (5AQ) have been recorded in the range 4000-400 and 3500-100 cm(-1), respectively. The complete vibrational assignment and...

Photochemistry of 5-aminoquinoline in protic and aprotic solvents

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 79(3) , 412-7, (2011)

Graphical abstract Photophysical/photochemical properties of 5-aminoquinoline (5AQ) have been investigated. In aprotic solvents, the spectra depend on the polarity. However, in protic solvents both th...

Related Compounds

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