5-Nitroquinoline

Names

[ CAS No. ]:
607-34-1

[ Name ]:
5-Nitroquinoline

[Synonym ]:
QUINOLINE,5-NITRO
5-Nitro-quinoline
MFCD00006790
EINECS 210-134-3
5-Nitroquinoline
Quinoline, 5-nitro-
5-Nitro-chinolin

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
323.1±17.0 °C at 760 mmHg

[ Melting Point ]:
71-73 °C(lit.)

[ Molecular Formula ]:
C₉H₆N₂O₂

[ Molecular Weight ]:
174.156

[ Flash Point ]:
149.2±20.9 °C

[ Exact Mass ]:
174.042923

[ PSA ]:
58.71000

[ LogP ]:
1.86

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.682

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VC1850000

CHEMICAL NAME :: Quinoline, 5-nitro-

CAS REGISTRY NUMBER :: 607-34-1

BEILSTEIN REFERENCE NO. :: 0135179

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C9-H6-N2-O2

MOLECULAR WEIGHT :: 174.17

WISWESSER LINE NOTATION :: T66 BNJ GNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - mouse Fibroblast

DOSE/DURATION :: 500 umol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,521,1975

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332-H351

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R36/37/38;R40;R68

[ Safety Phrases ]:
S7-S22-S36-S45-S36/37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VC1850000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Prediction of Setschenow constants of N-heteroaromatics in NaCl solutions based on the partial charge on the heterocyclic nitrogen atom.

Environ. Sci. Pollut. Res. Int. 23 , 3399-405, (2016)

The solubilities of 19 different kinds of N-heteroaromatic compounds in aqueous solutions with different concentrations of NaCl were determined at 298.15 K with a UV-vis spectrophotometry and titratio...

The use of silver solid amalgam electrodes for voltammetric and amperometric determination of nitrated polyaromatic compounds used as markers of incomplete combustion.

ScientificWorldJournal 2012 , 231986, (2012)

Genotoxic nitrated polycyclic aromatic hydrocarbons (NPAHs) are formed during incomplete combustion processes by reaction of polycyclic aromatic hydrocarbons (PAHs) with atmospheric nitrogen oxides. 1...

Oxygen dependence of the cytotoxicity and metabolic activation of 4-alkylamino-5-nitroquinoline bioreductive drugs.

Br. J. Cancer 70(4) , 596-603, (1994)

The cytotoxic potency of 4-alkylamino-5-nitroquinoline drugs in AA8 cell cultures is enhanced up to 60-fold under hypoxia, with wide variations in selectivity for hypoxic cells observed for different ...