5-Amino-8-hydroxyquinoline

Names

[ Name ]:
5-Amino-8-hydroxyquinoline

[Synonym ]:
8-hydroxy-5-aminoquinoline
5-Amino-8-hydroxyquinoline
5-Amino-quinolin-8-ol
5-azanylquinolin-8-ol
5-Amino-8-quinolinol
5-Amino-chinolin-8-ol
8-Quinolinol,5-amino
5-amino-8-hydroxyquinoline dihydrocholride

Biological Activity

[Description]:

5-Amino-8-hydroxyquinoline (5A8HQ), a potential anticancer candidate, has promising proteasome inhibitory activity.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome

[References]

[1]. Ruankham W, et al. In silico and multi-spectroscopic analyses on the interaction of 5-amino-8-hydroxyquinoline and bovine serum albumin as a potential anticancer agent. Sci Rep. 2021 Oct 12;11(1):20187.

Chemical & Physical Properties

[ Density]:
1.363g/cm3

[ Boiling Point ]:
408.3ºC at 760 mmHg

[ Molecular Formula ]:
C₉H₈N₂O

[ Molecular Weight ]:
160.17300

[ Exact Mass ]:
160.06400

[ PSA ]:
59.14000

[ LogP ]:
2.10380

[ Vapour Pressure ]:
3E-07mmHg at 25°C

[ Index of Refraction ]:
1.759

Safety Information

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%