Methyl 2-furoate
Names
[ CAS No. ]:
611-13-2
[ Name ]:
Methyl 2-furoate
[Synonym ]:
Methyl 2-furoate
2-Furancarboxylic acid, methyl ester
methyl furan-2-carboxylate
Methyl furoate
Furancarboxylic acid, methyl ester
EINECS 210-254-6
MFCD00003236
Methyl furancarboxylate
Methyl 2-furoate
Biological Activity
[Description]:
[Related Catalog]:
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
181.3±0.0 °C at 760 mmHg
[ Melting Point ]:
36ºC
[ Molecular Formula ]:
C6H6O3
[ Molecular Weight ]:
126.110
[ Flash Point ]:
73.3±0.0 °C
[ Exact Mass ]:
126.031693
[ PSA ]:
39.44000
[ LogP ]:
0.99
[ Vapour Pressure ]:
0.9±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.463
[ Water Solubility ]:
slightly soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LV1950000
- CHEMICAL NAME :
- 2-Furoic acid, methyl ester
- CAS REGISTRY NUMBER :
- 611-13-2
- BEILSTEIN REFERENCE NO. :
- 0111110
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C6-H6-O3
- MOLECULAR WEIGHT :
- 126.12
- WISWESSER LINE NOTATION :
- T5OJ BVO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,869,1979 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 58,174,1936
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,869,1979
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H312-H315-H319-H335
[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R21/22;R36/37/38
[ Safety Phrases ]:
S26-S36-S36/37/39
[ RIDADR ]:
UN 2810 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
LV1950000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
29321900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2932190090
[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
Articles
Org. Lett. 7(24) , 5353-6, (2005)
[structure: see text] A short and enantioselective synthesis of cis-fused 5-oxofuro[2,3-b]furans, being found in many spongiane diterpenoid natural products, is reported starting from inexpensive meth...
Asymmetric synthesis of both enantiomers of arteludovicinolide A.Org. Lett. 15(13) , 3420-3, (2013)
The first total synthesis of either enantiomer of Arteludovicinolide A and their biological evaluation is reported, featuring a new strategy for the asymmetric construction of γ-butyrolactones with st...