Velcorin
Names
[ CAS No. ]:
4525-33-1
[ Name ]:
Velcorin
[Synonym ]:
Velcorin
Carbonic acid, methoxycarbonyl methyl ester
EINECS 224-859-8
MFCD00008419
dicarbonic acid dimethyl ester
methoxycarbonyl methyl carbonate
Dimethyl pyrocarbonate
DMPC Dimethyl pyrocarbonate Pyrocarbonic acid dimethyl ester
Dimethyl dicarbonate
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
171.4±0.0 °C at 760 mmHg
[ Melting Point ]:
15-17ºC
[ Molecular Formula ]:
C4H6O5
[ Molecular Weight ]:
134.087
[ Flash Point ]:
80.0±0.0 °C
[ Exact Mass ]:
134.021530
[ PSA ]:
61.83000
[ LogP ]:
0.42
[ Vapour Pressure ]:
1.4±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.395
[ Water Solubility ]:
35g/l (decomposition)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HT0362500
- CHEMICAL NAME :
- Dicarbonic acid, dimethyl ester
- CAS REGISTRY NUMBER :
- 4525-33-1
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 711 mg/m3/4H
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545284 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 mg/m3/6H/5D-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545284
Safety Information
[ Symbol ]:
GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302 + H312-H314-H330
[ Precautionary Statements ]:
P260-P280-P284-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T
[ Risk Phrases ]:
R21/22
[ Safety Phrases ]:
18-26-28-36/37/39-38-45
[ RIDADR ]:
UN 2927 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
HT0362500
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2920909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2920909090
[ Summary ]:
2920909090 esters of other inorganic acids of non-metals (excluding esters of hydrogen halides) and their salts; their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Biochim. Biophys. Acta 1848(2) , 712-20, (2014)
The surrounding environment has significant consequences for the structural and functional properties of membrane proteins. While native structure and function can be reconstituted in lipid bilayer me...
Investigating the role of GXXXG motifs in helical folding and self-association of plasticins, Gly/Leu-rich antimicrobial peptides.Biophys. Chem. 196 , 40-52, (2014)
Plasticins (PTC) are dermaseptin-related antimicrobial peptides characterized by a large number of leucine and glycine residues arranged in GXXXG motifs that are often described to promote helix assoc...
Comparison of [corrected] actin- and glass-supported phospholipid bilayer diffusion coefficients.Biophys. J. 108(8) , 1946-53, (2015)
The formation of biomimetic lipid membranes has the potential to provide insights into cellular lipid membrane dynamics. The construction of such membranes necessitates not only the utilization of app...