CGP 7930

Names

[ Name ]:
CGP 7930

[Synonym ]:
cgp 7930

Biological Activity

[Description]:

CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> GABA Receptor

[References]

[1]. Urwyler S, et al. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol. 2001; 60(5):963-71.

Chemical & Physical Properties

[ Density]:
0.971g/cm3

[ Boiling Point ]:
364.7ºC at 760mmHg

[ Molecular Formula ]:
C₁₉H₃₂O₂

[ Molecular Weight ]:
292.45600

[ Flash Point ]:
152.6ºC

[ Exact Mass ]:
292.24000

[ PSA ]:
40.46000

[ LogP ]:
4.54820

Safety Information

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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