Neopentyl glycol
Names
[ CAS No. ]:
126-30-7
[ Name ]:
Neopentyl glycol
[Synonym ]:
Neopentyl glycol (NPG)
2,2-Bis(hydroxymethyl)propane
1,3-Propanediol, 2,2-dimethyl-
NPG Glycol,Neopentylglycol
2,2-Dihydroxy-2,2-dimethylpropane
2,2-dimethylpropane-1,3-diol
Neopentyl glycol
EINECS 204-781-0
2,2-Dimethyl-1,3-propanediol
MFCD00004685
Chemical & Physical Properties
[ Density]:
1.06
[ Boiling Point ]:
208 ºC
[ Melting Point ]:
122-128 ºC
[ Molecular Formula ]:
C5H12O2
[ Molecular Weight ]:
104.148
[ Flash Point ]:
107.2±0.0 °C
[ Exact Mass ]:
104.083733
[ PSA ]:
40.46000
[ LogP ]:
-0.34
[ Vapour density ]:
3.6 (vs air)
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.445
[ Stability ]:
Stable. Incompatible with strong oxidizing agents, acetic anhydride, acid chlorides, moisture. Combustible.
[ Water Solubility ]:
830 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TY5775000
- CHEMICAL NAME :
- 1,3-Propanediol, 2,2-dimethyl-
- CAS REGISTRY NUMBER :
- 126-30-7
- BEILSTEIN REFERENCE NO. :
- 0605291
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C5-H12-O2
- MOLECULAR WEIGHT :
- 104.17
- WISWESSER LINE NOTATION :
- Q1X1&1&1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 39000 ppm/6H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83578 No. of Facilities: 497 (estimated) No. of Industries: 11 No. of Occupations: 37 No. of Employees: 15135 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83578 No. of Facilities: 367 (estimated) No. of Industries: 11 No. of Occupations: 14 No. of Employees: 6957 (estimated) No. of Female Employees: 1200 (estimated)
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H318
[ Precautionary Statements ]:
P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36
[ Safety Phrases ]:
S26-S36-S39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
TY5775000
[ HS Code ]:
2905399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2905399090
[ Summary ]:
2905399090 other diols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%
Articles
Protein Expr. Purif. 116 , 159-66, (2015)
CFTR is unique among ABC transporters as the only one functioning as an ion channel and from a human health perspective because mutations in its gene cause cystic fibrosis. Although considerable advan...
Understanding the cellular function of TRPV2 channel through generation of specific monoclonal antibodies.PLoS ONE 8 , e85392, (2014)
Transient receptor potential vanilloid 2 (TRPV2) is a Ca(2+)-permeable nonselective cation channel proposed to play a critical role in a wide array of cellular processes. Although TRPV2 surface expres...
Occurrence of short chain aliphatic diols in human blood: identification by gas chromatography-mass spectrometry.Clin. Chim. Acta 155(2) , 117-22, (1986)
Patients attending a general hospital for various reasons were screened for raised serum gamma glutamyltransferase (gamma-GT) and positive blood alcohol concentration (BAC). The results served as obje...