57717-80-3

57717-80-3 structure

Name: CGP 7930
Chemical Name: 3-(3,5-ditert-butyl-4-hydroxyphenyl)-2,2-dimethyl-1-propanol
CAS Number: 57717-80-3
Molecular Formula: C₁₉H₃₂O₂
Molecular Weight: 292.45600
Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
Create Date: 2018-12-23 09:19:14
Modify Date: 2024-02-02 10:06:43
CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons[1].

Name	3-(3,5-ditert-butyl-4-hydroxyphenyl)-2,2-dimethyl-1-propanol
Synonyms	cgp 7930

Description	CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
References	[1]. Urwyler S, et al. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol. 2001; 60(5):963-71.

WGK Germany	3

56189-68-5

~99%

57717-80-3

128-39-2

57717-80-3

87-97-8

57717-80-3

128-39-2

126-30-7

1516-94-5

57717-80-3

Literature: Krysin; Pustovskikh; Koptyug Russian Journal of General Chemistry, 2010 , vol. 80, # 10 p. 2001 - 2006

Precursor 4
56189-68-5 128-39-2 87-97-8 126-30-7
DownStream 0