Osthenol
Names
Biological Activity
[Description]:
Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B[1].
[Related Catalog]:
[Target]
hMAO-A:0.26 μM (Ki)
hMAO-A:0.74 μM (IC50)
[References]
Chemical & Physical Properties
[ Density]:
1.203g/cm3
[ Boiling Point ]:
422.8ºC at 760 mmHg
[ Molecular Formula ]:
C14H14O3
[ Molecular Weight ]:
230.25900
[ Flash Point ]:
184.1ºC
[ Exact Mass ]:
230.09400
[ PSA ]:
50.44000
[ LogP ]:
3.00730
[ Vapour Pressure ]:
9.53E-08mmHg at 25°C
[ Index of Refraction ]:
1.595
[ Storage condition ]:
2-8℃