NEP-In-1

Names

[ CAS No. ]:
465527-94-0

[ Name ]:
NEP-In-1

Biological Activity

[Description]:

NEP-IN-1 is a neutral endopeptidase (NEP) inhibitor with IC50 of 2 nM for dNEP.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Neprilysin
Research Areas >> Neurological Disease

[Target]

IC50: 2 nM (NEP)[1]


[In Vitro]

NEP-IN-1 (Compound 30) is a selective inhibitor of neutral endopeptidase for the treatment of female sexual arousal disorder[1].

[References]

[1]. Pryde DC, et al. Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder. Bioorg Med Chem. 2007 Jan 1;15(1):142-59.


[Related Small Molecules]

Sacubitril/valsartan (LCZ696) | AHU 377 | Sacubitrilat | Phosphoramidon disodium salt | Racecadotril | Candoxatril | NEP-IN-2 | SQ28603

Chemical & Physical Properties

[ Molecular Formula ]:
C21H30ClNO4

[ Molecular Weight ]:
395.92

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds