8-Bromoguanosine

Names

[ Name ]:
8-Bromoguanosine

[Synonym ]:
8-Bromoguanosine
Guanosine, 8-bromo-
8-Bromo-9-β-D-ribofuranosylguanine
2-Amino-8-bromo-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydropurin-6-one
T56 BN DN FVM INJ CE HZ B- BT5OTJ CQ DQ E1Q &&β-D-Ribo Form
2-Amino-8-bromoinosine.
2-Amino-8-bromo-6-hydroxypurine riboside
EINECS 223-677-6
2-Amino-8-bromo-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1H-purin-6(9H)-one
MFCD00037985

Biological Activity

[Description]:

8-Bromoguanosine is a purine nucleoside, a brominated derivative of guanosine. 8-Bromoguanosine can reduce the conformational heterogeneity of RNA to enhance its function[1][2][3].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

8-Bromoguanosine (16-18 h) induces cytotoxic activity to YAC cells[2]. 8-Bromoguanosine (18 h) induces macrophage cytolytic activity to P815 cells[2].

Chemical & Physical Properties

[ Density]:
2.6±0.1 g/cm3

[ Boiling Point ]:
774ºC at 760mmHg

[ Melting Point ]:
222°C

[ Molecular Formula ]:
C₁₀H₁₂BrN₅O₅

[ Molecular Weight ]:
362.137

[ Flash Point ]:
421.9ºC

[ Exact Mass ]:
361.002167

[ PSA ]:
159.77000

[ LogP ]:
-0.08

[ Vapour Pressure ]:
1.73E-17mmHg at 25°C

[ Index of Refraction ]:
1.986

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
S22-S24/25

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%