8-Allyloxyguanosine

Names

[ Name ]:
8-Allyloxyguanosine

[Synonym ]:
8-(2-Propenyl)oxyguanosine
8-(allyloxy)-2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one

Biological Activity

[Description]:

8-Allyloxyguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.892 g/cm3

[ Molecular Formula ]:
C₁₃H₁₇N₅O₆

[ Molecular Weight ]:
339.30

[ Exact Mass ]:
339.11800

[ PSA ]:
168.74000

[ Index of Refraction ]:
1.789

8-Allyloxyguanosine

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds