2-Iodoadenosine

Names

[ Name ]:
2-Iodoadenosine

[Synonym ]:
2-iodo-2',3'-O-isopropylidene-adenosine
Adenosine,2-iodo
MFCD01320413
2-idodadenosine
6-Amino-2-iodo-9-(β-D-ribofuranosyl)purine
2-Iodoadenosine
2-Iodo-D-adenosine
Adenosine, 2-iodo-
2-IODO ADENOSINE

Biological Activity

[Description]:

2-Iodoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Density]:
2.7±0.1 g/cm3

[ Boiling Point ]:
776.3±70.0 °C at 760 mmHg

[ Melting Point ]:
200ºC (dec.)

[ Molecular Formula ]:
C₁₀H₁₂IN₅O₄

[ Molecular Weight ]:
393.14

[ Flash Point ]:
423.3±35.7 °C

[ Exact Mass ]:
392.993378

[ PSA ]:
139.54000

[ LogP ]:
-1.04

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.994

[ Storage condition ]:
Refrigerator, Under Inert Atmosphere

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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