TNK2-IN-1

Names

[ Name ]:
TNK2-IN-1

Biological Activity

[Description]:

TNK2-IN-1 is a TNK2 inhibitor. TNK2-IN-1 has an IC50 of 224 nM for TNK2. TNK2-IN-1 can be used for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase

[Target]

TNK2:224 nM (IC50)

[In Vitro]

TNK2-IN-1 (compound 21) has an EC50 of 0.15 μM for cell viability of Ba/F3 cells expressing TNK2 D163E[1].

[References]

[1]. Li Z, et al. Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing. Bioorg Med Chem Lett. 2020 Oct 1;30(19):127456.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₄N₆O₂

[ Molecular Weight ]:
416.48

Related Compounds

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