2574456-10-1

2574456-10-1 structure

2574456-10-1 structure

Name: TNK2-IN-1
Chemical Name: TNK2-IN-1
CAS Number: 2574456-10-1
Molecular Formula: C₂₃H₂₄N₆O₂
Molecular Weight: 416.48
Catalog: Signaling Pathways Metabolic Enzyme/Protease Tyrosinase
Create Date: 2022-02-21 11:30:33
Modify Date: 2024-01-18 22:42:36
TNK2-IN-1 is a TNK2 inhibitor. TNK2-IN-1 has an IC50 of 224 nM for TNK2. TNK2-IN-1 can be used for the research of cancer[1].

Name	TNK2-IN-1

Description	TNK2-IN-1 is a TNK2 inhibitor. TNK2-IN-1 has an IC50 of 224 nM for TNK2. TNK2-IN-1 can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase
Target	TNK2:224 nM (IC50)
In Vitro	TNK2-IN-1 (compound 21) has an EC50 of 0.15 μM for cell viability of Ba/F3 cells expressing TNK2 D163E[1].
References	[1]. Li Z, et al. Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing. Bioorg Med Chem Lett. 2020 Oct 1;30(19):127456.

Molecular Formula	C₂₃H₂₄N₆O₂
Molecular Weight	416.48