Docosapentaenoic acid (22:5(n-3))
Names
[ CAS No. ]:
24880-45-3
[ Name ]:
Docosapentaenoic acid (22:5(n-3))
[Synonym ]:
7,10,13,16,19-Docosapentaenoic acid, (7Z,10Z,13Z,16Z,19Z)-
(7Z,10Z,13Z,16Z,19Z)-7,10,13,16,19-Docosapentaenoic acid
all-cis-7,10,13,16,19-Docosapentaenoic acid
CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID
Docosapentaenoic acid (22:5(n-3))
(7Z,10Z,13Z,16Z,19Z)-Docosa-7,10,13,16,19-pentaenoic acid
(7Z,10Z,13Z,16Z,19Z)-Docosapentaenoic acid
MFCD00156103
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Human Endogenous Metabolite
[References]
[1]. Sinclair HM, et al. Essential fatty acids in perspective. Hum Nutr Clin Nutr. 1984 Jul;38(4):245-60.
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
442.2±24.0 °C at 760 mmHg
[ Molecular Formula ]:
C22H34O2
[ Molecular Weight ]:
330.504
[ Flash Point ]:
338.9±18.0 °C
[ Exact Mass ]:
330.255890
[ PSA ]:
37.30000
[ LogP ]:
7.26
[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C
[ Index of Refraction ]:
1.509
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JR1320000
- CHEMICAL NAME :
- 7,10,13,16,19-Docosapentaenoic acid, (all Z)-
- CAS REGISTRY NUMBER :
- 24880-45-3
- LAST UPDATED :
- 199106
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C22-H34-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >20 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 20,801,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >20 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 20,801,1989
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
JR1320000
Articles
J. Nat. Prod. 69 , 700-3, (2006)
Natural product drug discovery efforts frequently utilize noncellular screening assays. Fatty acids are commonly found in natural product extracts, and some have been shown to interfere with noncellul...
Regulation of the biosynthesis of 4,7,10,13,16-docosapentaenoic acid.Biochem. J. 326 ( Pt 2) , 425-30, (1997)
It is now established that fatty acid 7,10,13,16-22:4 is metabolized into 4,7,10,13,16-22:5 as follows: 7,10,13,16-22:4-->9,12,15, 18-24:4-->6,9,12,15,18-24:5-->4,7,10,13,16-22:5. Neither C24 fatty ac...
The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase.J. Biol. Chem. 266(30) , 19995-20000, (1991)
The hypothesis that the last step in the biosynthesis of 4,7,10,13,16,19-22:6 from linolenate is catalyzed by an acyl-CoA-dependent 4-desaturase has never been evaluated by direct experimentation. Whe...