Fucose

Names

[ Name ]:
Fucose

[Synonym ]:
EINECS 219-452-7
MFCD00135607
6-DEOXY-β-L-GALACTOSE
L-(-)-fucose 6-Deoxy-L-galactoseL-(-)-Rhodeose
L-(？)-Fucose
(-)-Fucose
(2S,3R,4R,5S)-2,3,4,5-Tétrahydroxyhexanal
L-GalactoMethylose
L-(-)-Flucose
6-deoxy-l-galactos
L-(−)-Fucose
6-Deoxy-L-galactose
L-(-)-Rhodeose
(-)-L-Fucose
Fucopyranose, L-
FUCOSE,L
6-Desoxygalactose
L-Fuc
L-Galactose, 6-deoxy-
L-(-)-Fucose
L-FUCOSE

Biological Activity

[Description]:

(-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions.

[Related Catalog]:

Research Areas >> Metabolic Disease

Research Areas >> Infection

Natural Products >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Becker DJ, et al. Fucose: biosynthesis and biological function in mammals. Glycobiology. 2003 Jul;13(7):41R-53R.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
399.1±35.0 °C at 760 mmHg

[ Melting Point ]:
150-153 °C(lit.)

[ Molecular Formula ]:
C₆H₁₂O₅

[ Molecular Weight ]:
164.156

[ Flash Point ]:
209.3±22.4 °C

[ Exact Mass ]:
164.068466

[ PSA ]:
97.99000

[ LogP ]:
-2.04

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.531

[ Storage condition ]:
-20°C Freezer

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
H2O: 0.1 g/mL, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2912491000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2912491000

[ Summary ]:
2912491000. other aldehyde-alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Rehmannia glutinosa (Gaertn.) DC. polysaccharide ameliorates hyperglycemia, hyperlipemia and vascular inflammation in streptozotocin-induced diabetic mice.

J. Ethnopharmacol. 164 , 229-38, (2015)

Rehmannia glutinosa (Gaertn.) DC. (RG) has been widely used as traditional Chinese herbal medicine for treatment of diabetes and its complications. The polysaccharide fraction of RG has been proposed ...

Fingerprinting profile of polysaccharides from Lycium barbarum using multiplex approaches and chemometrics.

Int. J. Biol. Macromol. 78 , 230-7, (2015)

Techniques including ultraviolet-visible spectra (UV), high performance size-exclusion chromatography (HPSEC), Fourier-transform infrared spectroscopy (FT-IR) and pre-column derivatization high-perfor...

An L-Fucose Operon in the Probiotic Lactobacillus rhamnosus GG Is Involved in Adaptation to Gastrointestinal Conditions.

Appl. Environ. Microbiol. 81 , 3880-8, (2015)

L-Fucose is a sugar present in human secretions as part of human milk oligosaccharides, mucins, and other glycoconjugates in the intestinal epithelium. The genome of the probiotic Lactobacillus rhamno...

Related Compounds

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