ChemR23-IN-1

Names

[ CAS No. ]:
2378640-10-7

[ Name ]:
ChemR23-IN-1

Biological Activity

[Description]:

ChemR23-IN-1 (compound 2) is a ChemR23 inhibitor with IC50s of 38 nM and 100 nM for human and mouse ChemR23, respectively. ChemR23-IN-1 inhibits chemotaxis of CAL-1 triggered by Chemerin in vitro[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[Target]

IC50: 38 nM (human ChemR23 ) and 100 nM (mouse ChemR23)[1]


[References]

[1]. Takamichi Imaizumi, et al. The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem. 2020 Sep 1;28(17):115622.

Chemical & Physical Properties

[ Molecular Formula ]:
C28H29N7O2

[ Molecular Weight ]:
495.58

Related Compounds

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