ChemR23-IN-4

Names

[ Name ]:
ChemR23-IN-4

Biological Activity

[Description]:

ChemR23-IN-4 (Compound 13) is a potent and orally efficacious ChemR23 inhibitor with an IC50 of 17 nM against human ChemR23[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

IC50: 17 nM (hChemR23)[1]

[References]

[1]. Imaizumi T, et al. The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem. 2020 Sep 1;28(17):115622.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₆N₆O₃

[ Molecular Weight ]:
482.53

Related Compounds

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