MARK-IN-4

Names

[ CAS No. ]:
1990492-86-8

[ Name ]:
MARK-IN-4

Biological Activity

[Description]:

MARK-IN-4 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of 1 nM. Inhibition of microtubule affinity regulating kinase (MARK) represents a potentially attractive means of arresting neurofibrillary tangle pathology in Alzheimer's disease[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> AMPK

Signaling Pathways >> PI3K/Akt/mTOR >> AMPK

Research Areas >> Neurological Disease

[References]

[1]. Sloman DL, et al. Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties. Bioorg Med Chem Lett. 2016;26(17):4362-4366.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₃N₇OS

[ Molecular Weight ]:
421.52

Safety Information

[ Hazard Codes ]:
Xi

MARK-IN-4

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds