2378640-10-7

2378640-10-7 structure
2378640-10-7 structure
  • Name: ChemR23-IN-1
  • Chemical Name: ChemR23-IN-1
  • CAS Number: 2378640-10-7
  • Molecular Formula: C28H29N7O2
  • Molecular Weight: 495.58
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2022-07-01 13:55:27
  • Modify Date: 2025-09-11 15:31:58
  • ChemR23-IN-1 (compound 2) is a ChemR23 inhibitor with IC50s of 38 nM and 100 nM for human and mouse ChemR23, respectively. ChemR23-IN-1 inhibits chemotaxis of CAL-1 triggered by Chemerin in vitro[1].

Name ChemR23-IN-1
Description ChemR23-IN-1 (compound 2) is a ChemR23 inhibitor with IC50s of 38 nM and 100 nM for human and mouse ChemR23, respectively. ChemR23-IN-1 inhibits chemotaxis of CAL-1 triggered by Chemerin in vitro[1].
Related Catalog
Target

IC50: 38 nM (human ChemR23 ) and 100 nM (mouse ChemR23)[1]

References

[1]. Takamichi Imaizumi, et al. The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem. 2020 Sep 1;28(17):115622.

Molecular Formula C28H29N7O2
Molecular Weight 495.58
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