ChemR23-IN-1

Modify Date: 2025-09-11 15:31:58

ChemR23-IN-1 structure	Common Name	ChemR23-IN-1
	CAS Number	2378640-10-7	Molecular Weight	495.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₂₉N₇O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ChemR23-IN-1

ChemR23-IN-1 (compound 2) is a ChemR23 inhibitor with IC50s of 38 nM and 100 nM for human and mouse ChemR23, respectively. ChemR23-IN-1 inhibits chemotaxis of CAL-1 triggered by Chemerin in vitro[1].

Name	ChemR23-IN-1

Description	ChemR23-IN-1 (compound 2) is a ChemR23 inhibitor with IC50s of 38 nM and 100 nM for human and mouse ChemR23, respectively. ChemR23-IN-1 inhibits chemotaxis of CAL-1 triggered by Chemerin in vitro[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	IC50: 38 nM (human ChemR23 ) and 100 nM (mouse ChemR23)[1]
References	[1]. Takamichi Imaizumi, et al. The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem. 2020 Sep 1;28(17):115622.

Molecular Formula	C₂₈H₂₉N₇O₂
Molecular Weight	495.58

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