N,N-diethyl-2-chloroacetamide
Names
[ CAS No. ]:
2315-36-8
[ Name ]:
N,N-diethyl-2-chloroacetamide
[Synonym ]:
CDEA
tl83
N-diethylacetaMide
MONOMETHYLFORMAMIDE TECH
EINECS 219-019-2
MFCD00000928
Acetamide, 2-chloro-N,N-diethyl-
α-Chloro-N,N-diethylacetamide
2-Chloro-N
diethyl 2-chloroacetamide
N-Chloroacetyldiethylamine
N,N-Diethyl-2-chloro
N,N-diethyl chloroacetamide
CHLOROACETYLDIETHYLAMINE
N,N-Diethylchloroacetamide
2-chloro-N,N-diethyl-acetamide
2-Chloro-N,N-diethylacetamide
N,N-diethyl-2-chloroacetamide
N,N,-Diethylchloroacetamide
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
236.8±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C6H12ClNO
[ Molecular Weight ]:
149.619
[ Flash Point ]:
77.0±22.6 °C
[ Exact Mass ]:
149.060745
[ PSA ]:
20.31000
[ LogP ]:
0.55
[ Vapour Pressure ]:
0.0±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.449
[ Water Solubility ]:
soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AB5425000
- CHEMICAL NAME :
- Acetamide, 2-chloro-N,N-diethyl-
- CAS REGISTRY NUMBER :
- 2315-36-8
- BEILSTEIN REFERENCE NO. :
- 0605866
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C6-H12-Cl-N-O
- MOLECULAR WEIGHT :
- 149.64
- WISWESSER LINE NOTATION :
- G1VN2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 10,97,1965
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 315 mg/m3/4H
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 980 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 33(2),51,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 226 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 270 mg/m3/2H
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 175 mg/m3/4H
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H311-H315-H319-H330-H335
[ Precautionary Statements ]:
P260-P280-P284-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T+:Verytoxic;
[ Risk Phrases ]:
R21/22;R26;R36/37/38
[ Safety Phrases ]:
S45-S38-S36/37/39-S28A-S26-S28
[ RIDADR ]:
2810
[ RTECS ]:
AB5425000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
29241900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924199090
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
J. Am. Chem. Soc. 124(29) , 8644-52, (2002)
A new "super-extended cavity" tetraacetylcalix[4]pyrrole derivative was synthesized and characterized, and X-ray crystal structures of complexes bound to fluoride and acetonitrile were obtained. The b...
[Gas-chromatographic analysis of N,N-diethylchloracetamide in the air].Gig. Sanit. (5) , 57-9, (1989)
[Local and skin resorptive action of N,N-diethylchloracetamide].
Gig. Tr. Prof. Zabol. (2) , 51-2, (1989)