N,N-diethyl-2-chloroacetamide

Modify Date: 2025-08-21 22:12:16

N,N-diethyl-2-chloroacetamide Structure
N,N-diethyl-2-chloroacetamide structure
Common Name N,N-diethyl-2-chloroacetamide
CAS Number 2315-36-8 Molecular Weight 149.619
Density 1.0±0.1 g/cm3 Boiling Point 236.8±0.0 °C at 760 mmHg
Molecular Formula C6H12ClNO Melting Point N/A
MSDS Chinese USA Flash Point 77.0±22.6 °C
Symbol GHS06
GHS06
Signal Word Danger

 Names

Name cdea
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 236.8±0.0 °C at 760 mmHg
Molecular Formula C6H12ClNO
Molecular Weight 149.619
Flash Point 77.0±22.6 °C
Exact Mass 149.060745
PSA 20.31000
LogP 0.55
Vapour Pressure 0.0±0.4 mmHg at 25°C
Index of Refraction 1.449
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB5425000
CHEMICAL NAME :
Acetamide, 2-chloro-N,N-diethyl-
CAS REGISTRY NUMBER :
2315-36-8
BEILSTEIN REFERENCE NO. :
0605866
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C6-H12-Cl-N-O
MOLECULAR WEIGHT :
149.64
WISWESSER LINE NOTATION :
G1VN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 10,97,1965
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
315 mg/m3/4H
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
980 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 33(2),51,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
226 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
270 mg/m3/2H
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
175 mg/m3/4H
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H302-H311-H315-H319-H330-H335
Precautionary Statements P260-P280-P284-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes T+:Verytoxic;
Risk Phrases R21/22;R26;R36/37/38
Safety Phrases S45-S38-S36/37/39-S28A-S26-S28
RIDADR 2810
RTECS AB5425000
Packaging Group III
Hazard Class 6.1
HS Code 29241900

 Synthetic Route

~98%

N,N-diethyl-2-chloroacetamide Structure

N,N-diethyl-2-c...

CAS#:2315-36-8

Literature: Hilton; Motherwell; Potier; Pradet; Selwood Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 9 p. 2239 - 2242

~%

N,N-diethyl-2-chloroacetamide Structure

N,N-diethyl-2-c...

CAS#:2315-36-8

Literature: European Journal of Medicinal Chemistry, , vol. 41, # 8 p. 985 - 990

~%

N,N-diethyl-2-chloroacetamide Structure

N,N-diethyl-2-c...

CAS#:2315-36-8

Literature: Chemistry of Natural Compounds, , vol. 48, # 6 p. 1047 - 1053 Khim. Prir. Soedin., , vol. 48, # 6 p. 924 - 929,6

~%

N,N-diethyl-2-chloroacetamide Structure

N,N-diethyl-2-c...

CAS#:2315-36-8

Literature: Bulletin de la Societe Chimique de France, , p. 1414,1416

~%

N,N-diethyl-2-chloroacetamide Structure

N,N-diethyl-2-c...

CAS#:2315-36-8

Literature: Bulletin de la Societe Chimique de France, , p. 1528 - 1532

~%

N,N-diethyl-2-chloroacetamide Structure

N,N-diethyl-2-c...

CAS#:2315-36-8

Literature: Doklady Chemistry, , vol. 171, p. 1184 - 1187 Doklady Akademii Nauk SSSR, , vol. 171, p. 1116 - 1119

~%

N,N-diethyl-2-chloroacetamide Structure

N,N-diethyl-2-c...

CAS#:2315-36-8

Literature: Chemische Berichte, , vol. 76, p. 87

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles6

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Fluoride-selective binding in a new deep cavity calix[4]pyrrole: experiment and theory.

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A new "super-extended cavity" tetraacetylcalix[4]pyrrole derivative was synthesized and characterized, and X-ray crystal structures of complexes bound to fluoride and acetonitrile were obtained. The b...

[Gas-chromatographic analysis of N,N-diethylchloracetamide in the air].

Gig. Sanit. (5) , 57-9, (1989)

[Local and skin resorptive action of N,N-diethylchloracetamide].

Gig. Tr. Prof. Zabol. (2) , 51-2, (1989)

 Synonyms

CDEA
tl83
N-diethylacetaMide
MONOMETHYLFORMAMIDE TECH
EINECS 219-019-2
MFCD00000928
Acetamide, 2-chloro-N,N-diethyl-
α-Chloro-N,N-diethylacetamide
2-Chloro-N
diethyl 2-chloroacetamide
N-Chloroacetyldiethylamine
N,N-Diethyl-2-chloro
N,N-diethyl chloroacetamide
CHLOROACETYLDIETHYLAMINE
N,N-Diethylchloroacetamide
2-chloro-N,N-diethyl-acetamide
2-Chloro-N,N-diethylacetamide
N,N-diethyl-2-chloroacetamide
N,N,-Diethylchloroacetamide
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