STING agonist-1(compound 3)trihydrochloride

Names

[ CAS No. ]:
2138299-34-8

[ Name ]:
STING agonist-1(compound 3)trihydrochloride

Biological Activity

[Description]:

diABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist.

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> STING

Research Areas >> Inflammation/Immunology

[Target]

STING[1].

[In Vivo]

diABZI STING agonist-1 (trihydrochloride) activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting−/− mice, confirming that diABZI STING agonist-1 (trihydrochloride) STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].

[References]

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.

[Related Small Molecules]

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₂H₅₄Cl₃N₁₃O₇

[ Molecular Weight ]:
959.32

STING agonist-1(compound 3)trihydrochloride

Names

Biological Activity

Chemical & Physical Properties

Related Compounds