STING agonist compound 3

Names

[ CAS No. ]:
2138299-33-7

[ Name ]:
STING agonist compound 3

Biological Activity

[Description]:

diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist.

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> STING

Research Areas >> Inflammation/Immunology

[Target]

STING[1].

[In Vivo]

diABZI STING agonist-1 activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting−/− mice, confirming that diABZI STING agonist-1 induces STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].

[References]

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.

[Related Small Molecules]

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₂H₅₁N₁₃O₇

[ Molecular Weight ]:
849.94

STING agonist compound 3

Names

Biological Activity

Chemical & Physical Properties

Related Compounds