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TVP1022 (mesylate)

Names

[ CAS No. ]:
202464-88-8

[ Name ]:
TVP1022 (mesylate)

[Synonym ]:
TVP1022 (mesylate)

Biological Activity

[Description]:

TVP1022 mesylate is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor.

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase
Research Areas >> Neurological Disease

[References]

[1]. Ertracht O, et al. The cardioprotective efficacy of TVP1022 in a rat model of ischaemia/reperfusion. Br J Pharmacol. 2011 Jun;163(4):755-69.

[2]. Berdichevski A, et al. TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements. J Pharmacol Exp Ther. 2010 Feb;332(2):413-20.


[Related Small Molecules]

Phenelzine (sulfate) | trans-2-Phenylcyclopropylamine hemisulfate salt | Clorgyline hydrochloride | Rosmarinic acid | pargyline hydrochloride | GSK-LSD1 Dihydrochloride | Rasagiline mesylate | Mofegiline hydrochloride | Paeonol | Iproniazid (phosphate) | Safinamide | TVP1022 | Minaprine | Nialamide | Desmethoxyyangonin

Chemical & Physical Properties

[ Molecular Formula ]:
C13H17NO3S

[ Molecular Weight ]:
267.34400

[ Exact Mass ]:
267.09300

[ PSA ]:
74.78000

[ LogP ]:
2.87240

[ Storage condition ]:
2-8℃

Related Compounds