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SPDB-DM4

Names

[ CAS No. ]:
1626359-62-3

[ Name ]:
SPDB-DM4

Biological Activity

[Description]:

SPDB-DM4 is a drug-linker conjugate for ADC by using the maytansinebased payload (DM4) via a SPDB linker, exhibiting potent anti-tumor activity.

[Related Catalog]:

Signaling Pathways >> Antibody-drug Conjugate >> Drug-Linker Conjugates for ADC
Research Areas >> Cancer

[References]

[1]. Puja Sapra, et al. Investigational antibody drug conjugates for solid tumors. Journal Expert Opinion on Investigational Drugs Volume 20, 2011-Issue 8.


[Related Small Molecules]

VcMMAE | Mertansine | dm1-smcc | McMMAF | Val-Cit-PAB-MMAE | Mc-MMAE | Acetylene-linker-Val-Cit-PABC-MMAE | Deruxtecan analog | Fmoc-Val-Cit-PAB-MMAE | Mc-MMAD | sulfo-SPDB-DM4

Chemical & Physical Properties

[ Molecular Formula ]:
C46H63ClN4O14S2

[ Molecular Weight ]:
995.59

[ Storage condition ]:
2-8℃

Related Compounds