Boc-Leu-OH.H2O

Names

[ Name ]:
Boc-Leu-OH.H2O

[Synonym ]:
N-Boc-L-leucine hydrate
(E)-N-{Hydroxy[(2-methyl-2-propanyl)oxy]methylene}-L-leucine
(S)-2-((tert-Butoxycarbonyl)amino)-4-methylpentanoic acid
MFCD00066067
L-LEUCINE-N-T-BOC:H2O
L-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-
BOC-LEU
boc-leu-oh.h20
EINECS 236-073-2
N-tert-butoxycarbonyl-L-leucine
BOC-L-LEUCINE-OH
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-leucine
N-tert-butyloxycarbonyl-L-leucine
BOC-L-Leucine
N(alpha)-t-butoxycarbonyl-L-leucine
Boc-Leu-OH,H2O
Boc-Leu-OH.H2O
N-Boc-L-leucine Monohydrate
L-Leucine, N-[(1,1-dimethylethoxy)hydroxymethylene]-, (E)-
BOC-L-LEU-OH
BOC-LEU-OH
N-(tert-Butoxycarbonyl)-L-leucine Monohydrate
Boc-Leu-OH Monohydrate
N-Boc-L-leucine

Biological Activity

[Description]:

Boc-L-Leu-OH is a leucine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
339.7±44.0 °C at 760 mmHg

[ Melting Point ]:
85-87 °C

[ Molecular Formula ]:
C₁₁H₂₁NO₄

[ Molecular Weight ]:
231.289

[ Flash Point ]:
159.2±28.4 °C

[ Exact Mass ]:
231.147064

[ PSA ]:
75.63000

[ LogP ]:
2.99

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.472

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi,Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nat. Chem. Biol. 5 , 45-52, (2009)

Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting tr...

In situ fabrication of cleavable peptide arrays on polydimethylsiloxane and applications for kinase activity assays.

Anal. Chim. Acta 865 , 53-9, (2015)

Polydimethylsiloxane (PDMS) is widely used for microfabrication and bioanalysis; however, its surface functionalization is limited due to the lack of active functional groups and incompatibility with ...

Concise synthesis of PM-94128 and Y-05460M-A.

J. Org. Chem. 74(19) , 7566-9, (2009)

The enantioselective total synthesis of PM-94128, a potent cytotoxin of microbial origin, was accomplished by a concise nine-step sequence of reactions in 14% overall yield from N-Boc-l-leucine. The s...