c-Fms-IN-8

Names

[ CAS No. ]:
1255303-58-2

[ Name ]:
c-Fms-IN-8

Biological Activity

[Description]:

c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms

[Target]

IC50: 9.1 nM (CSF-1R)[1].


[References]

[1]. Ikegashira K, et al. Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg Med Chem Lett. 2019 Jan 1;29(1):115-118.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H30N2O5

[ Molecular Weight ]:
462.54

Related Compounds