c-Fms-IN-12

Names

[ CAS No. ]:
2145102-33-4

[ Name ]:
c-Fms-IN-12

Biological Activity

[Description]:

c-Fms-IN-12 (Compound 4g) is an FMS kinase inhibitor. c-Fms-IN-12 can also inhibits c-KIT. c-Fms-IN-12 is a potential broad-spectrum anticancer agent against multiple cancer types. c-Fms-IN-12 induces A549 cell apoptosis[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Kit

[References]

[1]. Farag AK, et al. Diarylurea derivatives comprising 2,4-diarylpyrimidines: Discovery of novel potential anticancer agents via combined failed-ligands repurposing and molecular hybridization approaches. Bioorg Chem. 2020 Oct;103:104121.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H32N6O6

[ Molecular Weight ]:
572.61

Related Compounds