c-Fms-IN-10

Names

[ Name ]:
c-Fms-IN-10

Biological Activity

[Description]:

c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, an kinase inhibitor of FMS (Colony stimulating factor-1 receptor, CSF-1R) with IC50 of 2 nM.c-Fms-IN-10 has anti-tumor activity[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms

[References]

[1]. Kim YY， et al. Synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel FMS inhibitors. Bioorg Med Chem Lett. 2019 Jan 15;29(2):271-275.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₁₉N₇OS

[ Molecular Weight ]:
429.50

c-Fms-IN-10

Names

Biological Activity

Chemical & Physical Properties

Related Compounds