L-663581

Names

[ Name ]:
L-663581

[Synonym ]:
[14C]-FG 8205
7-chloro-5,6-dihydro-3-(5-isopropyl-1,2,4-oxadiazol-3-yl)-5-methyl-6-oxo-4H-imidazo<1,5-a><1,4>benzodiazepine
FG 8205

Biological Activity

[Description]:

L-663581 (FG-8205) is an agonist of benzodiazepine receptor, acting as a partial agonist at GABA A receptor[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> GABA Receptor

[References]

[1]. M D Tricklebank, et al. The pharmacological properties of the imidazobenzodiazepine, FG 8205, a novel partial agonist at the benzodiazepine receptor. Br J Pharmacol. 1990 Nov;101(3):753-61.

Chemical & Physical Properties

[ Density]:
1.5g/cm3

[ Boiling Point ]:
624.1ºC at 760mmHg

[ Molecular Formula ]:
C₁₇H₁₆ClN₅O₂

[ Molecular Weight ]:
357.79400

[ Flash Point ]:
331.3ºC

[ Exact Mass ]:
357.09900

[ PSA ]:
77.05000

[ LogP ]:
3.22260

[ Vapour Pressure ]:
1.7E-15mmHg at 25°C

[ Index of Refraction ]:
1.719

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.