1-(Furan-2-yl)ethanone

Names

[ Name ]:
1-(Furan-2-yl)ethanone

[Synonym ]:
methyl furan-2-yl ketone
2-acetyl-furan
2-acetyl-fura
2-ACETOFURONE
2-Acetalfurnan
T5OJ BV1
EINECS 214-757-1
1-(Furan-2-yl)ethanone
α-Methylfurfural
2-Acetylfuran
2-furylmethyl
1-(Furan-2-yl)ethan-1-one
1-(2-Furanyl)ethanone
2-Furyl methyl ketone
Furan, 2-acetyl-
Ethanone, 1- (2-furanyl)-
ACF
FEMA 3163
Ethanone, 1-(2-furanyl)-
furan-2-yl methyl ketone
Ketone, 2-furyl methyl
1-(2-Furyl)ethanone
2-furyl
MFCD00003242
2-furfuryl methyl ketone
ACETYLFURAN
Methyl 2-furyl ketone
1-(2-Furyl)ethan-1-one
2-ACETYL FURAN

Biological Activity

[Description]:

2-Acetylfuran (2-Furyl methyl ketone), an important flavour compound or intermediate in foods, is isolated from essential oils, sweet corn products, fruits and flowers. 2-Acetylfuran also can be formed from glucose and glycine by Maillard reaction. 2-Acetylfuran can be used to synthesis Cefuroxime[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Wang Y, et al. Amino acid-dependent formation pathways of 2-acetylfuran and 2,5-dimethyl-4-hydroxy-3[2H]-furanone in the Maillard reaction. Food Chemistry. 2009 Jul 1; 115(1):233-237.

[2]. Banerjee R, et, al. Medicinal significance of furan derivatives: A Review . International Journal of Research in Phytochemistry and Pharmacology. 2015, 5(3):48-57.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
183.4±0.0 °C at 760 mmHg

[ Melting Point ]:
26-28 °C(lit.)

[ Molecular Formula ]:
C₆H₆O₂

[ Molecular Weight ]:
110.111

[ Flash Point ]:
71.1±0.0 °C

[ Exact Mass ]:
110.036781

[ PSA ]:
30.21000

[ LogP ]:
0.52

[ Vapour Pressure ]:
0.8±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.463

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OB3870000

CHEMICAL NAME :: Ketone, 2-furyl methyl

CAS REGISTRY NUMBER :: 1192-62-7

BEILSTEIN REFERENCE NO. :: 0107909

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H6-O2

MOLECULAR WEIGHT :: 110.12

WISWESSER LINE NOTATION :: T5OJ BV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 4500 umol/L

REFERENCE :: CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 13,89,1981

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300-H311-H318-H332

[ Precautionary Statements ]:
P264-P280-P301 + P310-P305 + P351 + P338-P312

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R23/25;R36/37

[ Safety Phrases ]:
S26-S36/37/39-S45-S39-S38-S28A

[ RIDADR ]:
UN 2811 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
OB3870000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2932190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Quantification of furanic derivatives in fortified wines by a highly sensitive and ultrafast analytical strategy based on digitally controlled microextraction by packed sorbent combined with ultrahigh pressure liquid chromatography.

J. Chromatogr. A. 1381 , 54-63, (2015)

An improved, reliable and powerful analytical strategy based on digitally controlled microextraction by packed sorbent (MEPS) combined with ultrahigh pressure liquid chromatography (UHPLC) was validat...

Dose-dependent increase in 2,5-hexanedione in the urine of workers exposed to n-hexane.

Int. Arch. Occup. Environ. Health 63(4) , 285-91, (1991)

The concentrations of 2,5-hexanedione (2,5-HD), an n-hexane metabolite, and 2-acetylfuran (2-AF) were measured in urine samples from 123 workers who had predominantly been exposed to n-hexane vapor an...

2-Acetylfuran, a confounder in urinalysis for 2,5-hexanedione as an n-hexane exposure indicator.

Int. Arch. Occup. Environ. Health 63(3) , 213-9, (1991)

The apparent amount of 2,5-hexanedione, a biomarker of n-hexane expsoure in occupational health, in the urine of both exposed and non-exposed subjects varied not only as a function of the pH at which ...