L-Lysine, N6-formyl-

Names

[ Name ]:
L-Lysine, N6-formyl-

[Synonym ]:
Nepsilon-ForMyl-L-lysine
N(6)-formyl-L-lysine
MFCD00037362
N-ε-FORMYL-L-LYSINE
H-Lys(For)-OH
Nε-Formyl-L-lysine
N-EPSILON-FORMYL-L-LYSINE

Biological Activity

[Description]:

Nε-Formyl-L-lysine is a lysine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.169g/cm3

[ Boiling Point ]:
438.5ºC at 760mmHg

[ Molecular Formula ]:
C₇H₁₄N₂O₃

[ Molecular Weight ]:
174.19800

[ Flash Point ]:
219ºC

[ Exact Mass ]:
174.10000

[ PSA ]:
92.42000

[ LogP ]:
1.04170

[ Vapour Pressure ]:
6.46E-09mmHg at 25°C

[ Index of Refraction ]:
3 ° (C=0.9, H2O)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Analysis of glycated and ascorbylated proteins by gas chromatography-mass spectrometry.

J. Agric. Food Chem. 50 , 5697-5703, (2002)

Proteins or poly-L-lysine which were incubated in the presence of ascorbic acid, dehydroascorbic acid (ascorbylation), or various sugars (glycation) were analyzed by gas chromatography-mass spectromet...

The isolation of Nepsilon-formyl-L-lysine from the reaction between formaldehyde and L-lysine and its identification by OPLC and NMR spectroscopy.

J. Pharm. Biomed. Anal. 3 , 343-349, (1985)

From the reaction between l-lysine and formaldehyde, Nepsilon-formyl-L-lysine was isolated by means of ion-exchange column chromatography. The identification of Nepsilon-formyl-L-lysine was carried ou...

Quantitative analysis of histone modifications: formaldehyde is a source of pathological n(6)-formyllysine that is refractory to histone deacetylases.

PLoS Genet. 9(2) , e1003328, (2013)

Aberrant protein modifications play an important role in the pathophysiology of many human diseases, in terms of both dysfunction of physiological modifications and the formation of pathological modif...

Related Compounds

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